Abstract
A novel approach was developed to prepare a highly porous hydrogel with superior salt- and pH-resisting properties. According to this method, synthetic comonomers, i.e. acrylic acid (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AMPS), were polymerized and crosslinked in the presence of hydrolyzed collagen as a natural backbone. The characterizations of hydrogels were investigated by swelling experiment, Fourier transform infrared (FT-IR) spectroscopy, acid-base titration and thermogravimetric analysis (TGA). Morphology of the samples was examined by scanning electron microscopy (SEM). Experimental results indicate that the hydrogel has an absorbency of 360 and 73–82 g/g for distilled water and saline solutions, respectively. Water absorbency slightly changes from pH 3 to 8 and interestingly is more than of that in distilled water (∼500 g/g). The hydrogel thus prepared was showing a better salt- and pH-resistance compared to collagen-g-PAA hydrogel due to the introduction of the AMPS segment and therefore is a suitable candidate for horticulture and tissue engineering applications.
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Pourjavadi, A., Kurdtabar, M. & Ghasemzadeh, H. Salt- and pH-Resisting Collagen-based Highly Porous Hydrogel. Polym J 40, 94–103 (2008). https://doi.org/10.1295/polymj.PJ2007042
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DOI: https://doi.org/10.1295/polymj.PJ2007042
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